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Shokri, Abdol Jabbar, Heidari, Hamed. (1403). Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D. هنرهای کاربردی, 5(1), 23-30. doi: 10.22075/ppam.2024.34628.1107
Abdol Jabbar Shokri; Hamed Heidari. "Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D". هنرهای کاربردی, 5, 1, 1403, 23-30. doi: 10.22075/ppam.2024.34628.1107
Shokri, Abdol Jabbar, Heidari, Hamed. (1403). 'Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D', هنرهای کاربردی, 5(1), pp. 23-30. doi: 10.22075/ppam.2024.34628.1107
Shokri, Abdol Jabbar, Heidari, Hamed. Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D. هنرهای کاربردی, 1403; 5(1): 23-30. doi: 10.22075/ppam.2024.34628.1107

Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D

Progress in Physics of Applied Materials
مقاله 4، دوره 5، شماره 1 - شماره پیاپی 8، مرداد 2025، صفحه 23-30    اصل مقاله (1.92 M)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.22075/ppam.2024.34628.1107
نویسندگان
Abdol Jabbar Shokri* 1؛ Hamed Heidari2
1Department of Science, Payame Noor University, Sananda, Iran
2Department of Physics, Varamin Region, Directorate of Education
تاریخ دریافت: 17 شهریور 1403،  تاریخ بازنگری: 13 مهر 1403،  تاریخ پذیرش: 20 مهر 1403 
چکیده
In this paper, we conducted a numerical study to investigate the role of magnetic nanoparticles (MNPs) in the treatment of cancerous tissues in three dimensional. First, we considered the governing equations associated with this method. Next, we utilized the finite element method (FEM) and Comsol Multiphysics software package to calculate parameters such as temperature distribution, generated heat, and the fraction of damage in tumor and normal tissues over a 40-minute period. The applied frequencies and current in the coil were 150 and 300 kHz and 550 A, respectively. Our calculations revealed that the maximum temperatures of the tumor at frequencies of 150 and 300 kHz were 45.4 and 47 degrees, respectively. These temperatures are sufficient to destroy cancer cells. Furthermore, the comparison of results at 150 and 300 kHz frequencies demonstrated that parameters such as temperature, heat, and degradation rate increase with the increase of frequency. Additionally, we found that the tumor damage at the end of the process for frequencies of 150 and 300 kHz was 100% in the center of the tumor, but reduced to 63% and 75% at the border, respectively.
کلیدواژه‌ها
Magnetic Hyperthermia؛ Magnetic Nanoparticles؛ Breast Cancer؛ Simulation؛ Comsol Multiphysics
مراجع
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