دانشگاه سمنان

 آمار

تعداد نشریات21
تعداد شماره‌ها691
تعداد مقالات10,035
تعداد مشاهده مقاله71,039,333
تعداد دریافت فایل اصل مقاله62,488,790
Shokri, Abdol Jabbar, Heidari, Hamed. (1403). Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D. هنرهای کاربردی, 5(1), 23-30. doi: 10.22075/ppam.2024.34628.1107
Abdol Jabbar Shokri; Hamed Heidari. "Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D". هنرهای کاربردی, 5, 1, 1403, 23-30. doi: 10.22075/ppam.2024.34628.1107
Shokri, Abdol Jabbar, Heidari, Hamed. (1403). 'Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D', هنرهای کاربردی, 5(1), pp. 23-30. doi: 10.22075/ppam.2024.34628.1107
Shokri, Abdol Jabbar, Heidari, Hamed. Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D. هنرهای کاربردی, 1403; 5(1): 23-30. doi: 10.22075/ppam.2024.34628.1107

Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D

Progress in Physics of Applied Materials
مقاله 4، دوره 5، شماره 1 - شماره پیاپی 8، مرداد 2025، صفحه 23-30    اصل مقاله (1.92 M)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.22075/ppam.2024.34628.1107
نویسندگان
Abdol Jabbar Shokri* 1؛ Hamed Heidari2
1Department of Science, Payame Noor University, Sananda, Iran
2Department of Physics, Varamin Region, Directorate of Education
تاریخ دریافت: 17 شهریور 1403،  تاریخ بازنگری: 13 مهر 1403،  تاریخ پذیرش: 20 مهر 1403 
چکیده
In this paper, we conducted a numerical study to investigate the role of magnetic nanoparticles (MNPs) in the treatment of cancerous tissues in three dimensional. First, we considered the governing equations associated with this method. Next, we utilized the finite element method (FEM) and Comsol Multiphysics software package to calculate parameters such as temperature distribution, generated heat, and the fraction of damage in tumor and normal tissues over a 40-minute period. The applied frequencies and current in the coil were 150 and 300 kHz and 550 A, respectively. Our calculations revealed that the maximum temperatures of the tumor at frequencies of 150 and 300 kHz were 45.4 and 47 degrees, respectively. These temperatures are sufficient to destroy cancer cells. Furthermore, the comparison of results at 150 and 300 kHz frequencies demonstrated that parameters such as temperature, heat, and degradation rate increase with the increase of frequency. Additionally, we found that the tumor damage at the end of the process for frequencies of 150 and 300 kHz was 100% in the center of the tumor, but reduced to 63% and 75% at the border, respectively.
کلیدواژه‌ها
Magnetic Hyperthermia؛ Magnetic Nanoparticles؛ Breast Cancer؛ Simulation؛ Comsol Multiphysics
مراجع
  1. Bañobre-López, M., Teijeiro, A. and Rivas, J., 2013. Magnetic nanoparticle-based hyperthermia for cancer treatment. Reports of Practical Oncology & Radiotherapy, 18(6), pp.397-400.
  2. Chenthamara, D., Subramaniam, S., Ramakrishnan, S.G., Krishnaswamy, S., Essa, M.M., Lin, F.H. and Qoronfleh, M.W., 2019. Therapeutic efficacy of nanoparticles and routes of administration. Biomaterials research, 23(1), p.20.
  3. Din, F.U., Aman, W., Ullah, I., Qureshi, O.S., Mustapha, O., Shafique, S. and Zeb, A., 2017. Effective use of nanocarriers as drug delivery systems for the treatment of selected tumors. International journal of nanomedicine, pp.7291-7309.
  4. Shokri, A.J., Tavakoli, M.H., Sabouri Dodaran, A. and Khezrabad, A., 2019. A numerical study of the effect of the number of turns of coil on the heat produced in the induction heating process in the 3d model. Iranian Journal of Physics Research, 18(3), pp.408-419.
  5. Wu, K. and Wang, J.P., 2017. Magnetic hyperthermia performance of magnetite nanoparticle assemblies under different driving fields. AIP Advances, 7(5).
  6. Shah, R.R., Davis, T.P., Glover, A.L., Nikles, D.E. and Brazel, C.S., 2015. Impact of magnetic field parameters and iron oxide nanoparticle properties on heat generation for use in magnetic hyperthermia. Journal of magnetism and magnetic materials, 387, pp.96-106.
  7. Briceño, S., Hernandez, A.C., Sojo, J., Lascano, L. and Gonzalez, G., 2017. Degradation of magnetite nanoparticles in biomimetic media. Journal of Nanoparticle Research, 19, pp.1-10.
  8. Liu, X., Zhang, Y., Wang, Y., Zhu, W., Li, G., Ma, X., Zhang, Y., Chen, S., Tiwari, S., Shi, K. and Zhang, S., 2020. Comprehensive understanding of magnetic hyperthermia for improving antitumor therapeutic efficacy. Theranostics, 10(8), p.3793.
  9. Mohapatra, J. and Liu, J.P., 2018. Rare-earth-free permanent magnets: the past and future. Handbook of magnetic materials, 27, pp.1-57.
  10. Dennis, C.L. and Ivkov, R., 2013. Physics of heat generation using magnetic nanoparticles for hyperthermia. International Journal of Hyperthermia, 29(8), pp.715-729.
  11. Dennis, C.L. and Ivkov, R., 2013. Physics of heat generation using magnetic nanoparticles for hyperthermia. International Journal of Hyperthermia, 29(8), pp.715-729.
  12. Shokri, A. J., Saeedyan, Sh., Heidari, H., Azizi, A., Gilani, Z., (2024). Two-dimensional simulation of breast tissue tumor treatment using magnetic nanoparticles' Journal of Experimental Animal Biology, 4(1), pp. 21-26.
  13. Salloum, M., Ma, R. and Zhu, L., 2008. An in-vivo experimental study of temperature elevations in animal tissue during magnetic nanoparticle hyperthermia. International Journal of Hyperthermia, 24(7), pp.589-601.
  14. Jordan, A. K., Maier-Hauff, J., 2007. Magnetic nanoparticles for intracranial thermotherapy Nanosci. Nanotechnol. pp. 4604–4606.
  15. Dughiero, F. and Corazza, S., 2005. Numerical simulation of thermal disposition with induction heating used for oncological hyperthermic treatment. Medical and Biological Engineering and Computing, 43, pp.40-46.
  16. Zhao Q. Wang L. Cheng R. Mao L. Arnold RD. Howerth EW. Chen ZG. Platt S., 2012. Magnetic nanoparticle-based hyperthermia for head & neck cancer in mouse models. Theranostics. Vol.12, pp.27–38.
  17. Byrd, B.K., Krishnaswamy, V., Gui, J., Rooney, T., Zuurbier, R., Rosenkranz, K., Paulsen, K. and Barth, R.J., 2020. The shape of breast cancer. Breast cancer research and treatment, 183, pp.403-410.
  18. Heidari, H., Tavakoli, M.H., Shokri, A., Mohamad Moradi, B., Mohammad Sharifi, O. and Asaad, M.J.M., 2020. 3D simulation of the coil geometry effect on the induction heating process in Czochralski crystal growth system. Crystal Research and Technology, 55(3), p.1900147.
  19. Tucci, C., Trujillo, M., Berjano, E., Iasiello, M., Andreozzi, A. and Vanoli, G.P., 2021. Pennes’ bioheat equation vs. porous media approach in computer modeling of radiofrequency tumor ablation. Scientific reports, 11(1), p.5272.
  20. Spirou, S.V., Basini, M., Lascialfari, A., Sangregorio, C. and Innocenti, C., 2018. Magnetic hyperthermia and radiation therapy: radiobiological principles and current practice. Nanomaterials, 8(6), p.401.
  21. Singh, S. and Repaka, R., 2017. Effect of different breast density compositions on thermal damage of breast tumor during radiofrequency ablation. Applied Thermal Engineering, 125, pp.443-451.
  22. Mamiya, H. and Jeyadevan, B., 2019. Design criteria of thermal seeds for magnetic fluid hyperthermia-from magnetic physics point of view. In Nanomaterials for magnetic and optical hyperthermia applications(pp. 13-39). Elsevier.
  23. Laurent, S., Dutz, S., Häfeli, U.O. and Mahmoudi, M., 2011. Magnetic fluid hyperthermia: focus on superparamagnetic iron oxide nanoparticles. Advances in colloid and interface science, 166(1-2), pp.8-23.
  24. Tang, Y., Flesch, R.C. and Jin, T., 2017. Numerical investigation of temperature field in magnetic hyperthermia considering mass transfer and diffusion in interstitial tissue. Journal of Physics D: Applied Physics, 51(3), p.035401.
  25. Cao, T.L., Le, T.A., Hadadian, Y. and Yoon, J., 2021. Theoretical analysis for using pulsed heating power in magnetic hyperthermia therapy of breast cancer. International Journal of Molecular Sciences, 22(16), p.8895.
آمار
تعداد مشاهده مقاله: 392
تعداد دریافت فایل اصل مقاله: 386


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب