Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D | ||
| Progress in Physics of Applied Materials | ||
| مقاله 4، دوره 5، شماره 1 - شماره پیاپی 8، مرداد 2025، صفحه 23-30 اصل مقاله (1.92 M) | ||
| نوع مقاله: Original Article | ||
| شناسه دیجیتال (DOI): 10.22075/ppam.2024.34628.1107 | ||
| نویسندگان | ||
| Abdol Jabbar Shokri* 1؛ Hamed Heidari2 | ||
| 1Department of Science, Payame Noor University, Sananda, Iran | ||
| 2Department of Physics, Varamin Region, Directorate of Education | ||
| چکیده | ||
| In this paper, we conducted a numerical study to investigate the role of magnetic nanoparticles (MNPs) in the treatment of cancerous tissues in three dimensional. First, we considered the governing equations associated with this method. Next, we utilized the finite element method (FEM) and Comsol Multiphysics software package to calculate parameters such as temperature distribution, generated heat, and the fraction of damage in tumor and normal tissues over a 40-minute period. The applied frequencies and current in the coil were 150 and 300 kHz and 550 A, respectively. Our calculations revealed that the maximum temperatures of the tumor at frequencies of 150 and 300 kHz were 45.4 and 47 degrees, respectively. These temperatures are sufficient to destroy cancer cells. Furthermore, the comparison of results at 150 and 300 kHz frequencies demonstrated that parameters such as temperature, heat, and degradation rate increase with the increase of frequency. Additionally, we found that the tumor damage at the end of the process for frequencies of 150 and 300 kHz was 100% in the center of the tumor, but reduced to 63% and 75% at the border, respectively. | ||
| کلیدواژهها | ||
| Magnetic Hyperthermia؛ Magnetic Nanoparticles؛ Breast Cancer؛ Simulation؛ Comsol Multiphysics | ||
| مراجع | ||
|
| ||
|
آمار تعداد مشاهده مقاله: 488 تعداد دریافت فایل اصل مقاله: 578 |
||
| تعداد نشریات | 22 |
| تعداد شمارهها | 723 |
| تعداد مقالات | 10,398 |
| تعداد مشاهده مقاله | 72,887,200 |
| تعداد دریافت فایل اصل مقاله | 64,565,820 |