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Numerical Investigation of the Separation of Microparticles inside the Microchannel Using the Vortices Caused by the ICEK Phenomenon | ||
| Journal of Heat and Mass Transfer Research | ||
| دوره 10، شماره 1 - شماره پیاپی 19، مرداد 2023، صفحه 31-42 اصل مقاله (922.17 K) | ||
| نوع مقاله: Full Length Research Article | ||
| شناسه دیجیتال (DOI): 10.22075/jhmtr.2023.29957.1419 | ||
| نویسندگان | ||
| Seyed Mohammad Ehsan Ghadamgahi؛ Mohammad Mohsen Shahmardan؛ Mohsen Nazari* ؛ Hamed Mansouri | ||
| Faculty of Mechanical Engineering, Shahrood University of Technology, Shahrood, iran | ||
| تاریخ دریافت: 28 بهمن 1401، تاریخ بازنگری: 16 تیر 1402، تاریخ پذیرش: 17 تیر 1402 | ||
| چکیده | ||
| One field of study in microfluidics is the control, trapping, and separation of microparticles suspended in fluid. In recent years, much research has been started in this field. Some of its applications are related to cell handling, viruses, and bacteria detection, checking and analyzing biological cells and DNA molecules, testing water quality, or checking impurities in water. One of the new methods in this field is using Induced-charge electrokinetic phenomena (ICEK) and dielectrophoresis force. In the Induced-charge electrokinetic phenomena, the property of polarization of a conductive surface located in an electric field causes vortices to be created on the conductive plate in the fluid. This conductive plate is called a floating electrode. In the present study, considering the Induced-charge electrokinetic phenomena, the dielectrophoresis force, and creating an outlet on the roof of the microchannel at the place where two vortices of the ICEK phenomenon meet (secondary outlet), the microparticles inside the fluid are separated in the desired ratio. The separation is such that after the microparticles reach the floating electrode, they are trapped in the ICEK flow vortex and separated through a secondary channel, which is placed crosswise and non-coplanar above the main channel. In the present study, yeast microparticles are suspended in a KCl electrolyte solution and injected into the microchannel by a syringe pump. The arbitrary adjustment of the percentage of conduction and separation of microparticles towards the secondary outlet by adjusting the parameters of the applied voltage and fluid inlet velocity to the microchip is one of the innovations of the present study. In the simulation results, we observed that for input velocities (20-120) (µm)/s, respectively, with applied voltages (150-330) V (to create an electric field in the floating electrode), 100% of the particles can be directed towards the secondary-outlet, and separated. To validate the simulation results, the results obtained from the simulation method of the present study have been compared with the results of previous works. | ||
| کلیدواژه‌ها | ||
| Induced charged electrokinetic؛ Microfluidics؛ Microparticles؛ Separation؛ Floating electrode | ||
| عنوان مقاله [English] | ||
| بررسی عددی جداسازی میکروذرات در میکروکانال با استفاده از گردابه‌های ناشی از پدیده ICEK | ||
| چکیده [English] | ||
| یکی از زمینه های مطالعه در حوزه میکروسیالات، کنترل، به دام انداختن و جداسازی ریزذرات معلق در سیال است. در سال های اخیر تحقیقات زیادی در این زمینه آغاز شده است. برخی از کاربردهای آن مربوط به جابجایی سلول، شناسایی ویروس ها و باکتری ها، بررسی و آنالیز سلول های بیولوژیکی و مولکول های DNA، آزمایش کیفیت آب یا بررسی ناخالصی های موجود در آب است. یکی از روش‌های جدید در این زمینه استفاده از پدیده الکتروکینتیک القایی (ICEK) و نیروی دی‌الکتروفورز است. در پدیده ی الکتروکینتیک القایی، خاصیت پلاریزاسیون یک سطح رسانا واقع در میدان الکتریکی باعث ایجاد گردابه بر روی صفحه رسانا در سیال می شود. این صفحه رسانا الکترود شناور نامیده می شود. در تحقیق حاضر با در نظر گرفتن پدیده الکتروکینتیک القایی، نیروی دی‌الکتروفورز و ایجاد یک خروجی بر روی سقف میکروکانال در محل برخورد دو گردابه پدیده ICEK (خروجی ثانویه)، میکروذرات داخل سیال از هم جدا می‌شوند. جداسازی به این صورت است که پس از رسیدن میکروذرات به الکترود شناور، در گردابهای پدیده ICEK محبوس شده و از طریق یک کانال ثانویه جدا می شوند که این کانال به صورت متقاطع و غیرهمسطح بالای کانال اصلی قرار گرفته است. در مطالعه حاضر، میکروذرات مخمر معلق در محلول الکترولیت KCl توسط پمپ سرنگی به میکروکانال تزریق می‌شوند. تنظیم دلخواه درصد هدایت و جداسازی میکروذرات به سمت خروجی ثانویه با تنظیم پارامترهای ولتاژ اعمالی و سرعت ورودی سیال به ریزتراشه، یکی از نوآوری های تحقیق حاضر است. در نتایج شبیه سازی مشاهده کردیم که برای سرعت های ورودی (20-120) (μm)/s، به ترتیب، با ولتاژ اعمالی (150-330) ولت (برای ایجاد میدان الکتریکی در الکترود شناور)، 100 درصد ذرات را می توان به سمت خروجی ثانویه هدایت و جداسازی کرد. برای اعتبارسنجی نتایج شبیه سازی، نتایج به دست آمده از روش شبیه سازی پژوهش حاضر با نتایج کارهای قبلی مقایسه شده است. | ||
| کلیدواژه‌ها [English] | ||
| الکتروکینتیک القایی, میکروسیالات, میکروذرات, جداسازی, الکترود شناور | ||
| مراجع | ||
|
[1] Chen, X.-M., Ren, Y., Liu, W., Feng, X., Jia, Y., Tao, Y. and Jiang, H., 2017. A Simplified Microfluidic Device for Particle Separation with Two Consecutive Steps: Induced Charge Electro-osmotic Prefocusing and Dielectrophoretic Separation. 89(17), pp.9583–9592.
[2] Zheng, H., 2013. Using molecular tweezers to move and image nanoparticles. Nanoscale, 5(10), p.4070–78.
[3] Sun, H., Ren, Y., Liu, W., Feng, X., Hou, L., Tao, Y. and Jiang, H., 2018. Flexible Continuous Particle Beam Switching via External-Field-Reconfigurable Asymmetric Induced-Charge Electroosmosis. 90(19), pp.11376–11384.
[4] Manz, A., Harrison, D.Jed., Verpoorte, E.M.J., Fettinger, James.C., Paulus, A., Lüdi, H. and Widmer, H.Michael., 1992. Planar chips technology for miniaturization and integration of separation techniques into monitoring systems. Journal of Chromatography A, 593(1-2), pp.253–258.
[5] Chen, D., Du, H. and Chee Kiang Tay, 2009. Rapid Concentration of Nanoparticles with DC Dielectrophoresis in Focused Electric Fields. 5(1), pp.55–60.
[6] Ho, C.-T., Lin, R.-Z., Chang, W.-Y., Chang, H.-Y. and Liu, C.-H., 2006. Rapid heterogeneous liver-cell on-chip patterning via the enhanced field-induced dielectrophoresis trap. Lab on a Chip, 6(6), p.724.
[7] Bazant, M.Z. and Squires, T.M., 2011. Induced-Charge Electrokinetic Phenomena. pp.221–297.
[8] Peng, C., Lazo, I., Shiyanovskii, S.V. and Lavrentovich, O.D., 2014. Induced-charge electro-osmosis around metal and Janus spheres in water: Patterns of flow and breaking symmetries. 90(5).
[9] Ren, Y., Liu, W., Liu, J., Tao, Y., Guo, Y. and Jiang, H., 2016. Particle rotational trapping on a floating electrode by rotating induced-charge electroosmosis. Biomicrofluidics, 10(5), p.054103.
[10] Ashkin, A., Dziedzic, J.M. and Yamane, T., 1987. Optical trapping and manipulation of single cells using infrared laser beams. Nature, 330(6150), pp.769–771.
[11] Pethig, R., 1996. Dielectrophoresis: Using Inhomogeneous AC Electrical Fields to Separate and Manipulate Cells. Critical Reviews in Biotechnology, 16(4), pp.331–348.
[12] Muller, T., Fiedler, S., Schnelle, T., Ludwig, K., Jung, H. and Fuhr, G., 1996. High frequency electric fields for trapping of viruses. Biotechnology Techniques, 10(4).
[13] Muller, T., Fiedler, S., Schnelle, T., Ludwig, K., Jung, H. and Fuhr, G., 1996. High frequency electric fields for trapping of viruses. Biotechnology Techniques, 10(4).
[14] Liddle, J.A. and Gallatin, G.M., 2011. Lithography, metrology and nanomanufacturing. Nanoscale, 3(7), p.2679.
[15] Zhao, C. and Yang, C., 2018. Continuous-flow trapping and localized enrichment of micro- and nano-particles using induced-charge electrokinetics. Soft Matter, 14(6), pp.1056–1066.
[16] Ding, H., Liu, W., Shao, J., Ding, Y., Zhang, L. and Niu, J., 2013. Influence of Induced-Charge Electrokinetic Phenomena on the Dielectrophoretic Assembly of Gold Nanoparticles in a Conductive-Island-Basedpp.:12093−12103.
[17] Wu Yupan, Ren, Y., Tao, Y., Hou, L. and Jiang, H., 2016. Large-Scale Single Particle and Cell Trapping based on Rotating Electric Field Induced-Charge Electroosmosis. 88(23), pp.11791–11798.
[18] Ren, Y., Liu, W., Jia, Y., Tao, Y., Shao, J., Ding, Y. and Jiang, H., 2015. Induced-charge electroosmotic trapping of particles. 15(10), pp.2181–2191.
[19] Tao, Y., Ren, Y., Liu, W., Wu Yupan, Jia, Y., Lang, Q. and Jiang, H., 2016. Enhanced particle trapping performance of induced charge electroosmosis. 37(10), pp.1326–1336.
[20] Ren, Y., Liu, J., Liu, W., Lang, Q., Tao, Y., Hu, Q., Hou, L. and Jiang, H., 2016. Scaled particle focusing in a microfluidic device with asymmetric electrodes utilizing induced-charge electroosmosis. Lab on a Chip, 16(15), pp.2803–2812.
[21] Song, Y., Wang, C., Li, M., Pan, X. and Li, D., 2016. Focusing particles by induced charge electrokinetic flow in a microchannel. ELECTROPHORESIS, 37(4), pp.666–675.
[22] Zhao, C. and Yang, C., 2018. Continuous-flow trapping and localized enrichment of micro- and nano-particles using induced-charge electrokinetics. Soft Matter, 14(6), pp.1056–1066.
[23] Ding, H., Liu, W., Shao, J., Ding, Y., Zhang, L. and Niu, J., 2013. Influence of Induced-Charge Electrokinetic Phenomena on the Dielectrophoretic Assembly of Gold Nanoparticles in a Conductive-Island-Based Microelectrode System, pp.12093–103.
[24] Chen, X.-M., Ren, Y., Hou, L., Feng, X., Jiang, T. and Jiang, H., 2019. Microparticle separation using asymmetrical induced-charge electro-osmotic vortices on an arc-edge-based floating electrode. 144(17), pp.5150–5163.
[25] Tavari T, Nazari M, Akbarzadeh P, Sepehry N, Nazari M., 2022. Investigation of electro-osmotic micro-pumps using electrical field gradient and asymmetric micro-electrodes: numerical modeling and experimental validation. Amirkabir journal of mechanical engineering, 54, pp.101–122.
[26] Mottaghi S, Nazari M, Nazari M, Sepehry N, Mahdavi A., 2021. Control of droplet size in a two-phase microchannel using PID controller: A novel experimental study. Amirkabir journal of mechanical engineering, 53, pp.4279–4292.
[27] Baylon-Cardiel, J.L., Jesús-Pérez, N.M., Chávez-Santoscoy, A.V. and Lapizco-Encinas, B.H., 2010. Controlled microparticle manipulation employing low frequency alternating electric fields in an array of insulators. 10(23), pp.3235–3242.
[28] Wu, Z. and Li, D., 2007. Mixing and flow regulating by induced-charge electrokinetic flow in a microchannel with a pair of conducting triangle hurdles. Microfluidics and Nanofluidics, 5(1), pp.65–76.
[29] Wu, Z. and Li, D., 2008. Micromixing using induced-charge electrokinetic flow. Electrochimica Acta, 53(19), pp.5827–5835.
[30] Tavari, T., Nazari, M., Meamardoost, S., Tamayol, A. and Samandari, M., 2022. A systematic overview of electrode configuration in electric‐driven micropumps. Electrophoresis, 43(13-14), pp.1476-1520.
[31] Tavari, T., Meamardoost, S., Sepehry, N., Akbarzadeh, P., Nazari, M., Hashemi, N.N. and Nazari, M., 2023. Effects of 3D electrodes arrangement in a novel AC electroosmotic micropump: Numerical modeling and experimental validation. Electrophoresis, 44(3-4), pp.450-461.
[32] Nazari, M., Rashidi, S., Abolfazli Esfahani, J. and Harmand, S., 2022. A novel electrokinetic micromixing system with conductive mixing-enclosure-A geometrical study. Journal of Heat and Mass Transfer Research, 9(1), pp.65-76.
[33] Nazari, M., Rashidi, S. and Esfahani, J.A., 2020. Effects of flexibility of conductive plate on efficiency of an induced-charge electrokinetic micro-mixer under constant and time-varying electric fields-A comprehensive parametric study. Chemical Engineering Science, 212, p.115335.
[34] Daghighi, Y., Gao, Y. and Li, D., 2011. 3D numerical study of induced-charge electrokinetic motion of heterogeneous particle in a microchannel. Electrochimica acta, 56(11), pp.4254-4262.
[35] Nazari, M., Chuang, P.-Y.A., Abolfazli Esfahani, J. and Rashidi, S., 2020. A comprehensive geometrical study on an induced-charge electrokinetic micromixer equipped with electrically conductive plates. International Journal of Heat and Mass Transfer, 146, p.118892.
[36] Azimi, S., Nazari, M. and Daghighi, Y., 2017. Developing a fast and tunable micro-mixer using induced vortices around a conductive flexible link. Physics of Fluids, 29(3), p.032004.
[37] Nazari, M., Rashidi, S. and Esfahani, J.A., 2019. Mixing process and mass transfer in a novel design of induced-charge electrokinetic micromixer with a conductive mixing-chamber. International Communications in Heat and Mass Transfer, 108, p.104293. | ||
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