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مروری بر اهمیت تحلیل متغیرهای خون شناسی و بافت خونساز در مطالعات سم شناسی آبزیان | ||
تحقیقات آزمایشگاهی دامپزشکی | ||
دوره 16، شماره 2 - شماره پیاپی 26، بهمن 1403، صفحه 130-115 اصل مقاله (739.76 K) | ||
نوع مقاله: مقاله پژوهشی | ||
شناسه دیجیتال (DOI): 10.22075/jvlr.2025.36330.1144 | ||
نویسندگان | ||
سارا مهدی زاده مود* 1؛ محمود احمدی همدانی2 | ||
1گروه بهداشت مواد غذایی و آبزیان، دانشکده دامپزشکی دانشگاه سمنان، سمنان، ایران | ||
2گروه علوم درمانگاهی دانشکده دامپزشکی دانشگاه سمنان دانشکده دامپزشکی دانشگاه سمنان، سمنان، ایران | ||
تاریخ دریافت: 03 آذر 1403، تاریخ بازنگری: 11 دی 1403، تاریخ پذیرش: 06 بهمن 1403 | ||
چکیده | ||
بررسی خونشناسی در ماهیها یکی از روشهای مرسوم برای ارزیابی وضعیت فیزیولوژیکی این آبزیان بهشمار میرود و بهطور عمده شامل اندازهگیری پارامترهایی مانند گلبولهای قرمز، گلبولهای سفید و پلاکتها در واحد حجم خون است. این رویکرد، ابزاری پایهای برای شناسایی اثرات مواد آلی و معدنی بر سلامت ماهیها محسوب میشود و اغلب با آنالیزهای بیوشیمیایی و آسیبشناسی بافتی همراه است. هزینه پایین و عدم نیاز به تجهیزات پیچیده آزمایشگاهی، از مزایای اصلی این روش بهشمار میآیند؛ هرچند دقت آن تا حد زیادی به مهارت و تجربه فرد انجامدهنده وابسته است. برای تکمیل آنالیزهای هماتولوژیکی استاندارد، ارزیابی ترکیب سلولی و فعالیت بافت خونساز نیز پیشنهاد میشود. با این حال، اطلاعات محدودی درباره تأثیر زنوبیوتیکها (مواد شیمیایی خارجی) بر ساختار سلولی بافت خونساز بخش قدامی کلیه ماهیها وجود دارد؛ مسئلهای که بر ضرورت پژوهشهای بیشتر در این زمینه تأکید میکند. ازاینرو، بهرهگیری همزمان از آنالیزهای هماتولوژیک و هماتوپوئتیک میتواند ارزیابی جامعتر و دقیقتری از آثار مواد سمی بر سلامت ماهیها ارائه دهد. | ||
کلیدواژهها | ||
آبزیان؛ پارامترهای خونی؛ بافت خونساز؛ سم شناسی | ||
عنوان مقاله [English] | ||
Critical Role of Hematological and Hematopoietic Tissue Evaluations in Aquatic Toxicology | ||
نویسندگان [English] | ||
Sara Mehdizadeh Mood1؛ Mahmood Ahmadi-Hamedani2 | ||
1Food Hygiene and Aquatic Animal department,Faculty of Veterinary Medicine, Semnan University, Semnan, Iran | ||
2Clinical science department, Faculty of Veterinary Medicine,Semnan University, Semnan, Iran | ||
چکیده [English] | ||
Hematological assessment in fish is widely recognized as a standard approach to evaluate their physiological status, primarily involving measurements of red blood cells, white blood cells, and platelets per unit volume of blood. This method serves as a fundamental tool for detecting the impact of various organic and inorganic substances on fish health and is often supplemented by biochemical analyses and histopathological evaluations. Its major advantages include low cost and minimal need for complex laboratory equipment. However, the accuracy of hematological analyses is largely influenced by the skill and experience of the examiner. To enhance the reliability of standard hematological assessments, it is recommended to also evaluate the cellular composition and functional activity of hematopoietic tissue. Despite its importance, limited information is available regarding the effects of xenobiotics (foreign chemical compounds) on the cellular structure of the anterior kidney hematopoietic tissue in fish, underscoring the need for additional research. Therefore, the combined application of hematological and hematopoietic analyses can provide a more comprehensive and precise evaluation of toxic substances’ impacts on fish health. | ||
کلیدواژهها [English] | ||
Fish, Hematological parameters, Hematopoietic tissue, Toxicology | ||
مراجع | ||
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